Jing-Qiong Kang Selected Research

GABA Plasma Membrane Transport Proteins

10/2022	Astrocytic GABA transporter 1 deficit in novel SLC6A1 variants mediated epilepsy: Connected from protein destabilization to seizures in mice and humans.
1/2021	Genetic mosaicism, intrafamilial phenotypic heterogeneity, and molecular defects of a novel missense SLC6A1 mutation associated with epilepsy and ADHD.
1/2021	Common molecular mechanisms of SLC6A1 variant-mediated neurodevelopmental disorders in astrocytes and neurons.
12/2020	Endoplasmic reticulum retention and degradation of a mutation in SLC6A1 associated with epilepsy and autism.
10/2019	A missense mutation in SLC6A1 associated with Lennox-Gastaut syndrome impairs GABA transporter 1 protein trafficking and function.

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Jing-Qiong Kang Research Topics

Disease

20	Epilepsy (Aura) 10/2022 - 03/2009
9	Seizures (Absence Seizure) 10/2022 - 03/2006
9	Epileptic Syndromes 01/2021 - 09/2009
6	Generalized Epilepsy 10/2022 - 01/2006
5	Absence Epilepsy (Childhood Absence Epilepsy) 01/2021 - 10/2004
5	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2019 - 10/2010
5	Febrile Seizures (Febrile Seizure) 01/2017 - 10/2004
5	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2015 - 09/2003
4	Intellectual Disability (Idiocy) 01/2021 - 01/2019
4	Autistic Disorder (Autism) 01/2021 - 01/2013
4	Generalized Epilepsy with Febrile Seizures Plus 10/2010 - 02/2006
3	Brain Diseases (Brain Disorder) 01/2019 - 10/2016
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2021 - 01/2019
2	Neurodevelopmental Disorders 01/2021 - 01/2021
2	Autism Spectrum Disorder 12/2020 - 01/2019
2	Alzheimer Disease (Alzheimer's Disease) 02/2015 - 04/2004
2	Inborn Genetic Diseases (Disease, Hereditary) 09/2009 - 03/2009
2	Juvenile Myoclonic Epilepsy 01/2009 - 02/2006
2	Inflammation (Inflammations) 06/2004 - 04/2004
1	Neuroinflammatory Diseases 10/2020
1	Lennox Gastaut Syndrome 10/2019
1	Schizophrenia (Dementia Praecox) 01/2019
1	Cognitive Dysfunction 11/2018
1	Channelopathies 11/2017
1	Oculocutaneous albinism type 2 12/2016
1	Sudden Unexpected Death in Epilepsy 01/2016
1	Leukemia 01/2016
1	Ascorbic Acid Deficiency (Vitamin C Deficiency) 02/2015
1	Scurvy (Scorbutus) 02/2015
1	Autosomal Dominant Nocturnal Frontal Lobe Epilepsy 01/2009
1	Brain Ischemia (Cerebral Ischemia) 04/2004
1	Parkinson Disease (Parkinson's Disease) 04/2004
1	Hypoxia (Hypoxemia) 03/2003
1	Vascular System Injuries 12/2002
1	Nervous System Diseases (Neurological Disorders) 05/2002

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 10/2022 - 09/2009
8	Aminobutyrates (Aminobutyric Acid)IBA 10/2022 - 04/2014
8	GABA-A Receptors (GABA(A) Receptor)IBA 01/2013 - 10/2004
5	gamma-Aminobutyric Acid (GABA)IBA 10/2022 - 04/2014
5	GABA Plasma Membrane Transport ProteinsIBA 10/2022 - 10/2019
4	Nonsense Codon (Nonsense Mutation)IBA 10/2016 - 09/2009
3	Ion Channels (Ion Channel)IBA 10/2020 - 07/2015
3	Messenger RNA (mRNA)IBA 12/2016 - 03/2009
3	Ligand-Gated Ion ChannelsIBA 04/2014 - 01/2009
2	CytokinesIBA 10/2020 - 01/2017
2	Biological ProductsIBA 11/2017 - 09/2003
2	Pentylenetetrazole (Metrazol)IBA 01/2017 - 02/2015
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2016 - 07/2015
2	Cholinergic ReceptorsIBA 09/2009 - 01/2009
2	Terminator Codon (Termination Codon)IBA 09/2009 - 03/2009
2	Sodium Channels (Sodium Channel)IBA 03/2009 - 03/2006
2	Cysteine Proteases (Cysteine Protease)IBA 04/2004 - 12/2002
1	UbiquitinIBA 03/2022
1	Proteasome Endopeptidase Complex (Proteasome)IBA 03/2022
1	Mutant Proteins (Protein, Mutant)IBA 10/2020
1	ImmunosorbentsIBA 10/2020
1	EnzymesIBA 10/2020
1	stiripentolIBA 01/2019
1	N-Methylaspartate (NMDA)IBA 01/2019
1	Therapeutic UsesIBA 01/2019
1	Glutamic Acid (Glutamate)FDA Link 11/2018
1	Peptides (Polypeptides)IBA 01/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	ConvulsantsIBA 01/2017
1	RNA (Ribonucleic Acid)IBA 12/2016
1	Amyloid (Amyloid Fibrils)IBA 02/2015
1	Presenilin-1IBA 02/2015
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 02/2015
1	Kainic Acid (Kainate)IBA 02/2015
1	PotassiumIBA 09/2009
1	SodiumIBA 09/2009
1	delta Opioid Receptors (delta Opioid Receptor)IBA 02/2006
1	DNA (Deoxyribonucleic Acid)IBA 06/2004
1	PhosphatidylserinesIBA 06/2004
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2004
1	ElementsIBA 04/2004
1	Phosphotransferases (Kinase)IBA 04/2004
1	Apoptosis Regulatory ProteinsIBA 04/2004
1	Tyrosine (L-Tyrosine)FDA Link 10/2003
1	Non-Receptor Type 11 Protein Tyrosine PhosphataseIBA 10/2003
1	Free RadicalsIBA 03/2003
1	Erythropoietin FDA Link 05/2002

Therapy/Procedure

2	Therapeutics 01/2016 - 07/2015